Our company has extensive experience in solid state screening and research. We can provide you with one-stop API solid state research and development services according to the physical and chemical properties of APIs and the needs of the formulation team. If you have any needs, please feel free to contact us.
Our Services
The solid form of API can have a significant impact on the therapeutic efficacy of drugs as it can affect their solubility, dissolution rate, and bioavailability, all of which influence their performance in the patient's body after administration. Additionally, stable and reproducible solid forms of API are the foundation of drug formulations, including tablets, capsules, and inhalation products. Therefore, selecting the optimal solid form is becoming increasingly important in the development process of APIs.
Understanding the physical and chemical characteristics of the API, especially its optimal solid form, in the early stages of drug development can save you money and time. Our company aims to help pharmaceutical companies bring their candidate drugs to market and accelerate their time to market. We offer a wide range of services, including salt screening, co-crystal screening, polymorph screening, amorphous solid dispersion screening, crystallization process development, and optimization, and chiral resolution.
Our Techniques
| X-Ray powder diffraction (XRPD) | 1H NMR spectroscopy |
| Differential scanning calorimetry (DSC) | Ion chromatography (IC) |
| Thermogravimetric analysis (TGA) | Optical microscopy |
| Dynamic vapour sorption (DVS) | Hot stage microscopy (HSM) |
| Infra-red spectroscopy (FTIR) | Particle size distribution (PSD) |
| Ultraviolet spectroscopy (UV) | Raman spectroscopy |
| Gas chromatography (GC) | Karl Fischer titration |
| Single crystal X-ray diffraction (SC-XRD) | High-performance liquid chromatography (HPLC) |
| Transmission electron microscopy (TEM) | Specific surface area analysis (BET) and porosimetry |
Our Advantages
- One-stop service: Our company can assist you throughout the entire process of solid form selection, from initial screening, characterization, stability, and performance testing, to long-term stability testing.
- Advanced technology: Our company utilizes high-throughput screening technology to quickly identify the optimal solid form, effectively reducing manpower, time, cost, and the amount of required API for research.
- Highly qualified team: Our company has a team with a wealth of knowledge and expertise in the physical and chemistry characterization and screening of solid state APIs and API intermediates. We can customize a reasonable API solid state development plan according to your requirements.
Please kindly note that our services are for research use only.
