Active Pharmaceutical Ingredients (APIs) - The Backbone of Pharmaceutical Innovation

APIs are the primary ingredients responsible for the therapeutic effect of pharmaceutical products. Alfa Chemistry acts as a dependable ally in the worldwide pharmaceutical supply network by delivering top-grade APIs which maintain precision and safety while supporting effective drug development. Explore how our API offerings can serve as the fundamental building block for your next innovative pharmaceutical product.

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What are APIs?

APIs are the biologically active components in drugs that provide the intended therapeutic effects. These ingredients are formulated into medicines in various dosage forms, such as tablets, injections, ointments, and more. Without APIs, no drug would be effective.

Definition: APIs are responsible for the pharmacological effects of a drug, influencing its therapeutic efficacy.
Types: Depending on the therapeutic purpose, APIs can be antibiotics, anti-inflammatory agents, antivirals, analgesics, oncology drugs, and much more.
Development: The journey of an API from discovery to market involves rigorous research, testing, and manufacturing under stringent regulations.

How Are APIs Classified?

APIs can be categorized into two types, synthetic APIs and natural APIs, depending on the source of the API.

Synthetic APIs

Most modern APIs are synthetic; they are manufactured in a chemistry lab using precise chemical reactions and purification techniques. Synthetic APIs offer several advantages, including consistent quality, scalability, and the ability to create compounds that do not exist naturally.

Natural APIs

Some APIs are derived directly from natural materials, such as plants, animals, or minerals. For example, biological APIs (also known as biopharmaceuticals) are derived from living organisms or produced using biotechnological methods. These include proteins, peptides, nucleic acids, and other complex molecules that are essential for the treatment of diseases such as cancer, autoimmune diseases, and genetic disorders.

APIs can be categorized into various types based on the therapeutic area. Below are some of the main types we offer:

Please see our catalog for a variety of API specifications, including molecular structures, purity levels, and manufacturing details. You can also consult the experts at Alfa Chemistry to find out which API is best suited for your therapeutic area.

Customers Often Look For

The following selection showcases best-selling APIs known for high quality that cover an extensive range of therapeutic products. These active compounds combine high purity with potency and stability because they are produced using state-of-the-art processes and modern technology to achieve the best possible drug performance. Navigate through the links to find products that match your requirements.

Sulfadimethoxine sodium

PI1037509

Sulfadimethoxine

PI122112

Dexketoprofen Trometamol

PI156604794

Rasagiline Mesylate

PI161735791

Tenofovir Disoproxil Succinate

PI1637632973

Erlotinib Hydrochloride

PI183319699

Gefitinib

PI184475352

Gliclazide

PI21187984

Imatinib Mesylate

PI220127571

Ketoprofen

PI22071154

Nirmatrelvir

PI2628280408

Axitinib

PI319460850

Bezafibrate

PI41859670

Sitagliptin Hydrochloride

PI486459716

Ketoprofen Lysinate

PI57469780

Acyclovir

PI59277893

Sitagliptin phosphate

PI654671780

Cilostazol

PI73963721

Meropenem

PI96036032

Sulfadimethoxine sodium

Catalog: PI1037509

CAS Number: 1037-50-9

Molecular Formula: C12H13N4NaO4S

Molecular Weight: 332.31

Sulfadimethoxine

Catalog: PI122112

CAS Number: 122-11-2

Molecular Formula: C12H14N4O4S

Molecular Weight: 310.33

Dexketoprofen Trometamol

Catalog: PI156604794

CAS Number: 156604-79-4

Molecular Formula: C20H25NO6

Molecular Weight: 375.42

Rasagiline Mesylate

Catalog: PI161735791

CAS Number: 161735-79-1

Molecular Formula: C13H17NO3S

Molecular Weight: 267.34

Tenofovir Disoproxil Succinate

Catalog: PI1637632973

CAS Number: 1637632-97-3

Molecular Formula: C23H36N5O14P

Molecular Weight: 637.54

Erlotinib Hydrochloride

Catalog: PI183319699

CAS Number: 183319-69-9

Molecular Formula: C22H24ClN3O4

Molecular Weight: 429.90

Gefitinib

Catalog: PI184475352

CAS Number: 184475-35-2

Molecular Formula: C22H24ClFN4O3

Molecular Weight: 446.90

Gliclazide

Catalog: PI21187984

CAS Number: 21187-98-4

Molecular Formula: C15H21N3O3S

Molecular Weight: 323.41

Imatinib Mesylate

Catalog: PI220127571

CAS Number: 220127-57-1

Molecular Formula: C30H35N7O4S

Molecular Weight: 589.71

Ketoprofen

Catalog: PI22071154

CAS Number: 22071-15-4

Molecular Formula: C16H14O3

Molecular Weight: 254.28

Nirmatrelvir

Catalog: PI2628280408

CAS Number: 2628280-40-8

Molecular Formula: C23H32F3N5O4

Molecular Weight: 499.53

Axitinib

Catalog: PI319460850

CAS Number: 319460-85-0

Molecular Formula: C22H18N4OS

Molecular Weight: 386.47

Bezafibrate

Catalog: PI41859670

CAS Number: 41859-67-0

Molecular Formula: C19H20ClNO4

Molecular Weight: 361.82

Sitagliptin Hydrochloride

Catalog: PI486459716

CAS Number: 486459-71-6

Molecular Formula: C16H16ClF6N5O

Molecular Weight: 443.77

Ketoprofen Lysinate

Catalog: PI57469780

CAS Number: 57469-78-0

Molecular Formula: C22H28N2O5

Molecular Weight: 400.47

Acyclovir

Catalog: PI59277893

CAS Number: 59277-89-3

Molecular Formula: C8H11N5O3

Molecular Weight: 225.20

Sitagliptin phosphate

Catalog: PI654671780

CAS Number: 654671-78-0

Molecular Formula: C16H18F6N5O5P

Molecular Weight: 505.31

Cilostazol

Catalog: PI73963721

CAS Number: 73963-72-1

Molecular Formula: C20H27N5O2

Molecular Weight: 369.46

Meropenem

Catalog: PI96036032

CAS Number: 96036-03-2

Molecular Formula: C17H25N3O5S

Molecular Weight: 383.46

If you don't see your product here, we can still custom synthesize it. Contact us today to learn more about our products and how we can support your pharmaceutical needs.

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Small Molecule APIs Technology Platforms

With a focus on innovation, efficiency and green development, our small molecule APIs technology platform is dedicated to providing a range of cutting-edge key technologies for the synthesis of drugs.

Chiral Catalysis Technology Platform

Continuous Flow Technology Platform

Fluorine Chemistry Technology Platform

Biocatalysis Technology Platform

Photocatalysis Technology Platform

Catalyst Screening Platform

Comprehensive API Application Solutions

Therapeutic Applications

APIs are used in almost every area of medicine. From life-saving treatments to routine healthcare, they play a key role in drug formulation, for example:

Oncology: APIs for cancer treatment, such as chemotherapeutic agents, targeted therapies, and immunotherapies.
Neurology: APIs for the treatment of neurological disorders such as Alzheimer's, epilepsy, and Parkinson's.
Cardiology: APIs used in the treatment of hypertension, cholesterol-lowering drugs, and anti-arrhythmic therapy.
Anti-inflammatory: APIs that reduce inflammation in conditions such as arthritis, asthma, and autoimmune diseases.

View our API therapeutic areas

Drug Formulation

APIs are an integral part of drug design and delivery systems. They are formulated in a variety of ways to optimize therapeutic effects:

Oral tablets/capsules: APIs that are easily swallowed and absorbed in the gastrointestinal tract.
Injectables: APIs designed for rapid absorption into the bloodstream for immediate therapeutic effect.
Topical: APIs added to creams, gels, or ointments for topical treatment.

Understanding the relationship between the nature of the API (e.g., solubility, half-life) and the formulation is critical to ensuring the right therapeutic outcome.

Select Services：

Oral Dosage Form Development Nasal Dosage Forms Development

Injectable Dosage Form Development Topical Dosage Form Development

How to Place an Order for APIs?

Browse our product catalog and select your desired API(s).

Use our Quick Order form or contact a sales representative.

Receive a quote, confirm your order, and choose your preferred delivery method.

Get your high-quality APIs delivered directly to your facility.

Customer Reviews

Sarah M., Pharmaceutical Manufacturing Manager

"We’ve been sourcing APIs from Alfa Chemistry for the past two years, and we’ve been really impressed with the quality and consistency. Their products have helped us streamline our production processes. The documentation is always in order, and their timely delivery makes a huge difference in keeping our production schedules on track."

Dr. James L., R&D Director

"Alfa Chemistry has been our go-to supplier for high-quality APIs for several projects. The purity levels of their products have exceeded our expectations. I also appreciate the comprehensive certificates of analysis that come with each batch. It makes our compliance process much easier."

Linda W., Product Development Lead

"We’ve sourced multiple APIs from Alfa Chemistry for different drug formulations, and I’ve been thoroughly satisfied with their products. The customer service is great—they’re always quick to respond and provide any documentation or support needed."

Dr. Mark T., Senior Pharmacist

"We recently started using Alfa Chemistry for our API needs, and it’s been a positive experience. They offer a variety of options for different pharmaceutical applications. Shipping has always been on time, and we’ve had no issues with their products. Definitely recommend for any API sourcing."

API Services That Fit Your Needs

Preformulation Studies

API Process Development

API Analysis

Small Molecule APIs CDMO Services

What Our Customers Ask

Which APIs categories does your company supply?

Our product range includes numerous APIs across different therapeutic fields such as antibiotics along with analgesics, anti-inflammatory agents, cardiovascular medications, and additional categories. Our selection is designed to meet the needs of pharmaceutical manufacturers and researchers, whether you’re developing generic formulations or innovative treatments.

How can I be sure of the quality of the APIs you provide?

We prioritize quality in everything we do. Our APIs pass extensive testing protocols and adhere to established industry benchmarks to ensure purity, potency, and safety. Every batch includes a comprehensive COA to ensure transparency of quality parameters.

Can you supply APIs that are customized for particular formulations?

Yes! We recognize that each formulation requires individualized requirements. We provide customized API development together with tailored sourcing solutions for specific drug formulations. Our team collaborates with R&D teams to select APIs that fulfill your product specifications.

How quickly can I receive my order?

Our delivery service provides quick and dependable shipping to maintain your production timelines. Standard shipping times fluctuate based on both location and product availability, yet our commitment remains to deliver your order punctually. When expedited delivery or stringent deadlines are required, we can make special shipping arrangements for your order.

Will technical support be available to help with my API usage questions?

Absolutely! The technical support team stands ready to help with any questions regarding our APIs. Our team can guide you through formulations and compatibility checks between ingredients as well as help you meet regulatory compliance standards throughout the process.

What’s the minimum order quantity for APIs?

Our ordering options can be adjusted to match the requirements of both large manufacturers and small producers. The minimum order quantity differs between APIs, so we encourage you to reach out so we can discuss your particular needs. We strive to accommodate both small and bulk orders to suit your project needs.

Can you help me find the right API for my product development needs?

Yes! Our team provides expert assistance to help you select the best API for your project. Selecting the proper active ingredient is essential for your product's triumph, and we will lead you through this process by considering your therapeutic goals and formulation needs alongside regulatory requirements.

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