Drug conjugates, also known as conjugated drugs, are a class of biopharmaceuticals created by chemically linking a drug to a compatible molecule, such as an antibody, peptide, or polymer. This conjugation process enhances the targeted delivery of the drug to specific cells or tissues, thereby improving therapeutic efficacy and minimizing side effects. The most common form of drug conjugates is antibody-drug conjugates (ADCs), which combine the specificity of monoclonal antibodies with the potent cytotoxicity of small-molecule drugs. In the rapidly evolving field of pharmaceuticals, drug conjugates have emerged as a revolutionary approach to targeted therapy. Our drug conjugates technology platform leverages cutting-edge advancements in this domain to create highly effective and targeted treatments for various medical conditions.
Advantages of Drug Conjugates
Targeted Delivery: Drug conjugates are designed to specifically target diseased cells. This targeted approach ensures that higher concentrations of the drug reach the intended site of action.
Reduced Toxicity: Drug conjugates mitigate the effects on healthy cells by selectively targeting disease cells, thereby reducing systemic toxicity.
Increased Efficacy: By localizing the drug's action to specific sites within the body, drug conjugates can achieve higher therapeutic efficacy.
Improved Pharmacokinetics: Drug conjugates often exhibit improved pharmacokinetic profiles, including prolonged circulation time and better tissue penetration.
Access Our Drug Conjugates Technology Platform
Our drug conjugates technology platform is at the forefront of pharmaceutical innovation. It integrates state-of-the-art technology, cutting-edge research, and extensive expertise in drug conjugate development to develop and manufacture drug conjugates for various therapeutic applications. At present, we possess comprehensive capabilities to research, develop, and manufacture a wide range of drug conjugates.
Comprehensive Drug Conjugate Capabilities
Our platform excels in developing and manufacturing various types of drug conjugates, including:
- Antibody-drug conjugates (ADCs)
- Peptide drug conjugates (PDC)
- Small molecule-drug conjugates (SMDC)
- Immune-stimulating antibody conjugate (ISAC)
- Antibody-oligonucleotide conjugates (AOC)
- Radionuclide drug conjugates (RDC)
- Antibody fragment-drug conjugates (FDC)
- Aptamer drug conjugates (ApDC)
- Antibody cell drug conjugates (ACC)
- Virus-like drug conjugates (VDC)
Linker and Payload Development Capabilities
Our platform also boasts expertise in developing and manufacturing a wide variety of linkers, payloads, and related conjugation elements. This includes:
01Linkers
We specialize in the creation of stable linkers that ensure the payload is released only at the target site.
02Payloads
We can develop potent cytotoxic agents or other therapeutic molecules that serve as the "active" component of the drug conjugate.
03Chelators
Chelators are used in RDCs and other conjugates to securely bind radionuclides. Our expertise ensures the safe and effective incorporation of radioactive elements into therapeutic conjugates.
04Linker-Payload Conjugates
We develop the precise combination of linkers and payloads tailored for specific therapeutic needs, ensuring optimal efficacy and stability.
05Linker-Chelator Conjugates
We also can develop the integration of linkers with chelators, providing stable constructs that optimize radionuclide attachment and delivery.
Instruments and Equipment at Our Platform
Our state-of-the-art platform is equipped with advanced instruments that underpin our drug conjugate development process:
- High-performance liquid chromatography (HPLC)
- Mass spectrometry (MS)
- Nuclear magnetic resonance (NMR) spectroscopy
- Flow cytometry
- Dynamic light scattering (DLS)
- Biacore surface plasmon resonance (SPR)
- MALDI-TOF, ESI and LC-MS
- ...
Platform Advantages
01
Our team of seasoned scientists and researchers has deep knowledge in drug conjugate development from concept to clinical application.
02
Our use of cutting-edge instruments and methodologies allows us to offer precise and accurate analytical services, ensuring the highest-quality products.
03
We provide tailored solutions to meet specific research and therapeutic needs, enhancing the customization and specificity of drug conjugates.
04
We work closely with academic, industrial, and research partners to ensure our platform remains at the cutting edge of drug conjugate advancements.
Please kindly note that our services are for research use only.
