Our company is committed to providing comprehensive API process development services to help customers achieve efficient, cost-effective, environmentally friendly, and safe API production. We have the experience and expertise to support our customers from API route design, synthesis process optimization, solid state research and development, to process scale-up. If you have any needs, please feel free to contact us.
Our Services
API Route Design
In the early stages of drug development, finding a feasible synthetic route is crucial for successful drug development. Our team of experienced chemists can design efficient and sustainable synthetic routes to your target API. We will fully consider cost-effectiveness, safety, and environmental protection to ensure that your API can be synthesized in a feasible way.
API Synthesis Process Optimization
Optimizing the synthesis process can significantly improve the yield, purity, and stability of APIs. Through systematic experimental design and advanced analytical techniques, we can improve your synthetic steps to reduce waste, improve product quality, and reduce production costs. We also pay attention to the scalability of the synthesis process to ensure that it can proceed smoothly in subsequent process scale-up.
API Solid State Research and Development
The solid state properties of APIs have a significant impact on their stability, solubility, and bioavailability. We use advanced solid-state analytical techniques to study and optimize the crystalline shape, pharmaceutical salts, and physical properties of APIs. This helps to ensure the stability of APIs during formulation and production and ultimately improves the quality of the drug.
API Process Scale-Up (Pilot-Scale)
Once the synthetic route has been defined, we will assist you in successfully scaling up your lab-scale synthetic method to the pilot scale. We carefully design the scale-up experiments, taking into account factors such as reaction conditions, equipment selection, and safety, to ensure that stable and high-quality products can be obtained in industrial production. Our goal is to help you achieve a smooth transition from laboratory to commercial production.
Our Capabilities
| Chlorination reaction | Acylation reaction |
| Bromination reaction | Sulfonation reaction |
| Cyanide reaction | Reductive amination reaction |
| Asymmetric chiral synthesis | Grignard reaction |
| Friedel-Crafts reaction | Low-temperature reaction |
| Diels-Alder reaction | Carbonylation reaction |
| Reactions involving n-BuLi | Others |
Our Advantages
- Advanced technology: In order to meet the development needs of high-quality active pharmaceutical ingredients and provide the necessary data for regulatory approval, our company's analytical laboratory is equipped with various highly advanced technologies, capable of conducting precise evaluation and characterization of active pharmaceutical ingredients.
- Low cost and high efficiency: The extensive project experience of the our company team allows us to minimize process stages, increase yields and reduce time. In addition, we choose high-quality and cost-effective intermediates as raw materials for API synthesis, which can effectively reduce costs.
- Safety and environmental protection: our company applies green chemistry in the API synthesis process, adopts more environmentally friendly raw materials and processes to reduce the discharge of waste and harmful substances, and minimize the adverse impact on the environment.
Please kindly note that our services are for research use only.
