Biocatalysis Technology Platform

Platform Capacities

Our biocatalysis catalysis technology platform is a unique convergence of rich chemical knowledge and extensive experience in biotransformation. This synergy allows us to offer unparalleled biocatalytic solutions tailored to the pharmaceutical industry's demanding requirements. Moreover, we have established dedicated partnerships with top-tier biotechnology firms and academic institutions. These collaborations enable us to access the latest advancements in enzyme technology and biocatalysis and allow us to accumulate strong technical capabilities. So far, our platform has shown great capabilities:

• Extensive Enzyme Inventory: Our platform boasts a comprehensive inventory of over 600 different enzymes. This extensive collection includes hydrolases, ketone reductases, transaminases, amino acid dehydrogenases, amino acid acylases, imine reductases, ene reductases, nitrilases, oxynitrilases, monooxygenases, and many more.
• Specialized Applications and Expertise: Our platform has deep experience across several specialized applications of enzyme catalysis, including selective ester hydrolysis, asymmetric ketone reduction, asymmetric amine synthesis, asymmetric double bond reduction, etc.
• Scalability and Production Capabilities: Our platform is equipped to optimize reactions starting from milligram-scale laboratory experiments up to multi-ton industrial production. This capability ensures that our enzymatic solutions can be seamlessly transitioned from research and development to large-scale manufacturing with consistent quality and yield.

Services Provided

Backed by the strong strength and professional experienced team, our platform offers an extensive array of services.

• Enzyme Discovery and Development: Our team employs advanced bioinformatics tools, metagenomic libraries, and microbial screening techniques to identify novel enzymes from diverse biological sources.
• Custom Enzyme Development: By understanding the unique requirements of each project, we design enzymes with particular characteristics such as substrate specificity, stability under industrial conditions, and optimal catalytic activity.
• Molecular Modification and Directed Evolution: Our platform can employ tool such as site-directed mutagenesis, random mutagenesis, and recombination techniques to generate enzyme variants with improved properties, such as higher activity, better stability, and novel functionalities.
• High-Throughput Enzyme Screening: Our extensive enzyme inventory, along with high-throughput screening systems, allows us to quickly evaluate large libraries of enzyme variants.
• Preparation of Enzyme Formulation: Our platform can provide comprehensive enzyme formulation services. This includes the preparation of enzyme preparations in various forms, such as free enzymes, immobilized enzymes, and lyophilized powders.
• Enzyme Catalytic Process Development: We also support the development of enzyme catalytic processes tailored to specific pharmaceutical applications such as drug and intermediates development. Our team works closely with clients to design and optimize reaction conditions such as pH, temperature, substrate concentration, and cofactor requirements, ensuring maximum efficiency and yield.
• Pilot and Commercial-Scale Production: Our platform is equipped to scale up enzymatic processes from the lab to commercial-scale production.