Methotrexate

Cat. No.: PI59052

Product Details

CAS	59-05-2
Molecular Formula	C20H22N8O5
Molecular Weight	454.4
Standard	BP / EP / IP / USP
Uses	(1) Antineoplastic Agent: Methotrexate is combined with anti-TNF agents and shown effective in the management of patients with lymphoma (non-Hodgkin's type), carcinoma of the breast, small-cell carcinoma of the lung, epidermal tumors of the head and neck, and carcinoma of the ovary, lymphoblastic leukemia, head and neck cancer, osteosarcoma etc. (2) Rheumatoid Arthritis: Methotrexate is an FDA-approved folic acid antagonist indicated for the treatment of rheumatoid arthritis because of its high potency and efficacy in such patients; it can also be useful in patients with juvenile idiopathic arthritis. (3) Antifungal: Methotrexate is used off-lain cases of mycosis fungoides, dermatomyositis, pityriasis rubra pilaris, eczema, and sarcoidosis. (4) Other uses: Methotrexate is also safe and effective for patients with psoriasis, systemic lupus erythematosus, inflammatory bowel disease, vasculitis, and many other connective tissue diseases. The medication is also effective in patients with organ transplantation because of its anti-inflammatory and immunomodulatory activity.

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