Apixaban

Cat. No.: PI503612473

Description: Apixaban is an anti-clotting substance used to reduce the risk of stroke and systemic embolism (blood coagulation) in patients with nonvalvular atrial fibrillation (abnormal heart rhythm that is not caused by a heart valve problem).Atrial fibrillation (AF) occurs when the two upper chambers (atria) of the heart do not contract properly, allowing formation of blood clots, which can travel to other parts of the body. When a clot blocks blood flow to the heart or the brain, a heart attack or stroke can follow. Blood clots can wreak havoc in other parts of the body as well.

Product Details

CAS	503612-47-3
Trade Names	Eliquis
Synonyms	1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
Molecular Formula	C25H25N5O4
Molecular Weight	459.5
Available Formulations	Oral Solid
Technology	Synthetic
Available DMF/CEP/GMP	EU DMF, Korea DMF, US DMF
Uses	Reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. Prophylaxis of deep vein thrombosis (DVT) leading to pulmonary embolism (PE) in patients after a hip or knee replacement surgery. Treatment of DVT and PE to reduce the risk of recurrence.
Mechanism Of Action	Apixaban works by blocking the action of factor Xa, a protein that plays a key role in the blood clotting cascade. By blocking factor Xa, Apixaban prevents the formation of blood clots.
Appearance	White to pale-yellow powder

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